I've a hp 27" and using it's display partition feature I could possibly get away with it. one monster 30" monitor should be ok? tbh actually not sure whether a windows feature or it's the gfx card doing the partitioning? or the monitor itself? it does what it does, that's all I know but it works ok, I believe there are lots of different configs of screens and is a neat feature, sometimes!! t2w definitely doesn't like being pushed into partition screen and gets chopped to pieces. mine's currently set to two screens with a vertical split, I've not tried any other of the variations, mainly due to windows 8 and not being able to find sod all on the pc.
I'd still see a traditional multi monitor set up as best option, unless you're tight for desk space.