A much bigger question than many might think.
I respect TA-based stop initially - one that the TA indicates entry may have been right but the market has proven the move isn't going to work. Raghee Horner explains this very well in a clip on YouTube - she terms it the Point of Validity - it is the earliest price level that indicates the market is not going in your chosen direction, but, more than that, TA suggests its likely to accelerate from there in the opposite direction.Once I'm in profit, a TA-based target kicks in and I usually get fully out when this is hit.